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Non-CPAP therapies in obstructive sleep apnoea

Identifieur interne : 006893 ( Main/Exploration ); précédent : 006892; suivant : 006894

Non-CPAP therapies in obstructive sleep apnoea

Auteurs : W. J. Randerath [Allemagne] ; J. Verbraecken [Belgique] ; S. Andreas [Allemagne] ; G. Bettega [France] ; A. Boudewyns [Belgique] ; E. Hamans [Belgique] ; F. Jalbert [France] ; J. R. Paoli [France] ; B. Sanner [Allemagne] ; I. Smith [Royaume-Uni] ; B. A. Stuck [Allemagne] ; L. Lacassagne [France] ; M. Marklund [Suède] ; J. T. Maurer [Allemagne] ; J. L. Pepin [France] ; A. Valipour [Australie] ; T. Verse [Allemagne] ; I. Fietze [Allemagne]

Source :

RBID : Pascal:11-0225554

Descripteurs français

English descriptors

Abstract

In view of the high prevalence and the relevant impairment of patients with obstructive sleep apnoea syndrome (OSAS) lots of methods are offered which promise definitive cures for or relevant improvement of OSAS. This report summarises the efficacy of alternative treatment options in OSAS. An interdisciplinary European Respiratory Society task force evaluated the scientific literature according to the standards of evidence-based medicine. Evidence supports the use of mandibular advancement devices in mild to moderate OSAS. Maxillomandibular osteotomy seems to be as efficient as continuous positive airway pressure (CPAP) in patients who refuse conservative treatment. Distraction osteogenesis is usefully applied in congenital micrognathia or midface hypoplasia. There is a trend towards improvment after weight reduction. Positional therapy is clearly inferior to CPAP and long-term compliance is poor. Drugs, nasal dilators and apnoea triggered muscle stimulation cannot be recommended as effective treatments of OSAS at the moment. Nasal surgery, radiofrequency tonsil reduction, tongue base surgery, uvulopalatal flap, laser midline glossectomy, tongue suspension and genioglossus advancement cannot be recommended as single interventions. Uvulopalatopharyngoplasty, pillar implants and hyoid suspension should only be considered in selected patients and potential benefits should be weighed against the risk of long-term side-effects. Multilevel surgery is only a salvage procedure for OSA patients.


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Le document en format XML

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<title xml:lang="en" level="a">Non-CPAP therapies in obstructive sleep apnoea</title>
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<name sortKey="Stuck, B A" sort="Stuck, B A" uniqKey="Stuck B" first="B. A." last="Stuck">B. A. Stuck</name>
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<name sortKey="Lacassagne, L" sort="Lacassagne, L" uniqKey="Lacassagne L" first="L." last="Lacassagne">L. Lacassagne</name>
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<s1>Dept of Othodontics, Umea University</s1>
<s2>Umea</s2>
<s3>SWE</s3>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>Suède</country>
<wicri:noRegion>Umea</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Maurer, J T" sort="Maurer, J T" uniqKey="Maurer J" first="J. T." last="Maurer">J. T. Maurer</name>
<affiliation wicri:level="3">
<inist:fA14 i1="10">
<s1>Sleep Disorders Center, Dept of Otorhinolaryngology, Head and Neck Surgery, University Hospital Mannheim</s1>
<s2>Mannheim</s2>
<s3>DEU</s3>
<sZ>11 aut.</sZ>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<placeName>
<region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Mannheim</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Pepin, J L" sort="Pepin, J L" uniqKey="Pepin J" first="J. L." last="Pepin">J. L. Pepin</name>
<affiliation wicri:level="3">
<inist:fA14 i1="13">
<s1>EFCR Sleep and Respiration Unit, CHU Grenoble</s1>
<s2>Grenoble</s2>
<s3>FRA</s3>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Grenoble</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Valipour, A" sort="Valipour, A" uniqKey="Valipour A" first="A." last="Valipour">A. Valipour</name>
<affiliation wicri:level="3">
<inist:fA14 i1="14">
<s1>Otto-Wagner-Hospital, Dept of Respiratory and Critical Care Medicine, ,</s1>
<s2>Vienna</s2>
<s3>AUS</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<placeName>
<settlement type="city">Vienne (Autriche)</settlement>
<region nuts="2" type="province">Vienne (Autriche)</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Verse, T" sort="Verse, T" uniqKey="Verse T" first="T." last="Verse">T. Verse</name>
<affiliation wicri:level="1">
<inist:fA14 i1="15">
<s1>Dept of Otorhinolaryng========not;ology, Head and Neck Surgery, Asklepios Clinic Harburg, Harburg, Germany</s1>
<s2>Harburg</s2>
<s3>DEU</s3>
<sZ>17 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Harburg</wicri:noRegion>
<wicri:noRegion>Harburg</wicri:noRegion>
<wicri:noRegion>Harburg</wicri:noRegion>
</affiliation>
</author>
<author>
<name sortKey="Fietze, I" sort="Fietze, I" uniqKey="Fietze I" first="I." last="Fietze">I. Fietze</name>
<affiliation wicri:level="3">
<inist:fA14 i1="16">
<s1>Center of Interdisciplinary Sleep Medicine, Charite - Universitatsmedizin Berlin, CCM/CVK</s1>
<s2>Berlin</s2>
<s3>DEU</s3>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<placeName>
<region type="land" nuts="3">Berlin</region>
<settlement type="city">Berlin</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series>
<title level="j" type="main">The European respiratory journal</title>
<title level="j" type="abbreviated">Eur. respir. j.</title>
<idno type="ISSN">0903-1936</idno>
<imprint>
<date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt>
<title level="j" type="main">The European respiratory journal</title>
<title level="j" type="abbreviated">Eur. respir. j.</title>
<idno type="ISSN">0903-1936</idno>
</seriesStmt>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Device</term>
<term>Mandible</term>
<term>Osteotomy</term>
<term>Pneumology</term>
<term>Reduction</term>
<term>Sleep apnea syndrome</term>
<term>Stimulation</term>
<term>Surgery</term>
<term>Treatment</term>
<term>Weight</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr">
<term>Syndrome d'apnée du sommeil</term>
<term>Traitement</term>
<term>Mandibule</term>
<term>Dispositif</term>
<term>Ostéotomie</term>
<term>Chirurgie</term>
<term>Stimulation</term>
<term>Poids</term>
<term>Réduction</term>
<term>Pneumologie</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr">
<term>Chirurgie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">In view of the high prevalence and the relevant impairment of patients with obstructive sleep apnoea syndrome (OSAS) lots of methods are offered which promise definitive cures for or relevant improvement of OSAS. This report summarises the efficacy of alternative treatment options in OSAS. An interdisciplinary European Respiratory Society task force evaluated the scientific literature according to the standards of evidence-based medicine. Evidence supports the use of mandibular advancement devices in mild to moderate OSAS. Maxillomandibular osteotomy seems to be as efficient as continuous positive airway pressure (CPAP) in patients who refuse conservative treatment. Distraction osteogenesis is usefully applied in congenital micrognathia or midface hypoplasia. There is a trend towards improvment after weight reduction. Positional therapy is clearly inferior to CPAP and long-term compliance is poor. Drugs, nasal dilators and apnoea triggered muscle stimulation cannot be recommended as effective treatments of OSAS at the moment. Nasal surgery, radiofrequency tonsil reduction, tongue base surgery, uvulopalatal flap, laser midline glossectomy, tongue suspension and genioglossus advancement cannot be recommended as single interventions. Uvulopalatopharyngoplasty, pillar implants and hyoid suspension should only be considered in selected patients and potential benefits should be weighed against the risk of long-term side-effects. Multilevel surgery is only a salvage procedure for OSA patients.</div>
</front>
</TEI>
<affiliations>
<list>
<country>
<li>Allemagne</li>
<li>Australie</li>
<li>Belgique</li>
<li>France</li>
<li>Royaume-Uni</li>
<li>Suède</li>
</country>
<region>
<li>Angleterre</li>
<li>Angleterre de l'Est</li>
<li>Auvergne-Rhône-Alpes</li>
<li>Bade-Wurtemberg</li>
<li>Berlin</li>
<li>Collectivité territoriale de Corse</li>
<li>District de Karlsruhe</li>
<li>Rhône-Alpes</li>
<li>Vienne (Autriche)</li>
</region>
<settlement>
<li>Bastia</li>
<li>Berlin</li>
<li>Cambridge</li>
<li>Grenoble</li>
<li>Mannheim</li>
<li>Vienne (Autriche)</li>
</settlement>
<orgName>
<li>Université de Cambridge</li>
</orgName>
</list>
<tree>
<country name="Allemagne">
<noRegion>
<name sortKey="Randerath, W J" sort="Randerath, W J" uniqKey="Randerath W" first="W. J." last="Randerath">W. J. Randerath</name>
</noRegion>
<name sortKey="Andreas, S" sort="Andreas, S" uniqKey="Andreas S" first="S." last="Andreas">S. Andreas</name>
<name sortKey="Fietze, I" sort="Fietze, I" uniqKey="Fietze I" first="I." last="Fietze">I. Fietze</name>
<name sortKey="Maurer, J T" sort="Maurer, J T" uniqKey="Maurer J" first="J. T." last="Maurer">J. T. Maurer</name>
<name sortKey="Sanner, B" sort="Sanner, B" uniqKey="Sanner B" first="B." last="Sanner">B. Sanner</name>
<name sortKey="Stuck, B A" sort="Stuck, B A" uniqKey="Stuck B" first="B. A." last="Stuck">B. A. Stuck</name>
<name sortKey="Verse, T" sort="Verse, T" uniqKey="Verse T" first="T." last="Verse">T. Verse</name>
</country>
<country name="Belgique">
<noRegion>
<name sortKey="Verbraecken, J" sort="Verbraecken, J" uniqKey="Verbraecken J" first="J." last="Verbraecken">J. Verbraecken</name>
</noRegion>
<name sortKey="Boudewyns, A" sort="Boudewyns, A" uniqKey="Boudewyns A" first="A." last="Boudewyns">A. Boudewyns</name>
<name sortKey="Hamans, E" sort="Hamans, E" uniqKey="Hamans E" first="E." last="Hamans">E. Hamans</name>
</country>
<country name="France">
<region name="Auvergne-Rhône-Alpes">
<name sortKey="Bettega, G" sort="Bettega, G" uniqKey="Bettega G" first="G." last="Bettega">G. Bettega</name>
</region>
<name sortKey="Jalbert, F" sort="Jalbert, F" uniqKey="Jalbert F" first="F." last="Jalbert">F. Jalbert</name>
<name sortKey="Lacassagne, L" sort="Lacassagne, L" uniqKey="Lacassagne L" first="L." last="Lacassagne">L. Lacassagne</name>
<name sortKey="Paoli, J R" sort="Paoli, J R" uniqKey="Paoli J" first="J. R." last="Paoli">J. R. Paoli</name>
<name sortKey="Pepin, J L" sort="Pepin, J L" uniqKey="Pepin J" first="J. L." last="Pepin">J. L. Pepin</name>
</country>
<country name="Royaume-Uni">
<region name="Angleterre">
<name sortKey="Smith, I" sort="Smith, I" uniqKey="Smith I" first="I." last="Smith">I. Smith</name>
</region>
</country>
<country name="Suède">
<noRegion>
<name sortKey="Marklund, M" sort="Marklund, M" uniqKey="Marklund M" first="M." last="Marklund">M. Marklund</name>
</noRegion>
</country>
<country name="Australie">
<region name="Vienne (Autriche)">
<name sortKey="Valipour, A" sort="Valipour, A" uniqKey="Valipour A" first="A." last="Valipour">A. Valipour</name>
</region>
</country>
</tree>
</affiliations>
</record>

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